Evaluation of Drug Activities

Evaluation of Drug Activities

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Evaluation of Drug Activities: Pharmacometrics, Volume 2 provides information pertinent to the fundamental aspects of pharmacometrics. This book covers a variety of topics, including anticholinesterases, antitussives, cardioactive agents, diuretics, dermatological agents, and estrogens. Organized into 21 chapters, this volume begins with an overview of anticholinesterases and its pharmacological and physiological actions. This text then examines the diversity of methods for evaluating antitussive drugs, which is related to the complexity of cough reflexes. Other chapters consider tests for cardioactive substances of three general classes, namely, the cardiac glycosides, the coronary vasodilators, and the anti-arrhythmics. This book discusses as well the introduction of many diuretics into therapeutic practice during the past years bears witness to the convenience and success of the tests available for assessing drugs of this class. The final chapter deals with drugs affecting lipid levels in plasma. This book is a valuable resource for chemists, physiologists, pharmacologists, and clinicians.A diagram of the apparatus is shown in Fig. 1. Untreated ... After the control exposure the guinea pigs were permitted to recover and rest for 2a€“4 hr. At the end of ... The dose protecting 50% of guinea pigs could be determined (Green, 1953).

Title:Evaluation of Drug Activities
Author: D R Laurence, A. L. Bacharach
Publisher:Elsevier - 2013-10-22

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